NIPT - Non Invasive Prenatal Testing

NIPT is recommended by the NHS in genetic medicine because it offers expectant parents the latest in antenatal screening technology.

Everyone has their own personal reason for performing NIPT. For some, it is because they do not know their biological family or there may be a history of genetic disease within the family. For other parents may be due to a history of recurrent miscarriage or general pregnancy worries, for many women it is done purely for reassurance purposes. Whatever the reason we are sensitive to the situation.

NIPT is regarded as 'gold' standard within genetic screening and used to identify the risk of these conditions during pregnancy. All of our NIPT screening test options are provided by laboratories who use globally renowned Illumina technology.

NIPT is performed using a simple blood test from the mother with no risk to your unborn baby in comparison to one of the 'next step' diagnostic tests such as Amniocentesis or Chorionic Villus Sampling. Each test is performed using a simple maternal blood sample at one of our recommended clinics or at home.

If you are unsure which test is most suitable for you you can contact us. We offer unparalleled support to our customers.

TRIMESTER NIPT TEST ONE©

This NIPT test solely screens for Down's syndrome. For a deeper understanding of Down's syndrome please visit the NHS website or gain further support from The Down's Syndrome Association

Downs Syndrome (Trisomy 21)
Gender Determination (optional)
Available from 9 Weeks
Results within 10 Working Days and can be dependent on European public holidays

TRIMESTER NIPT TEST TWO©

This test provides analysis of chromosomes 13, 18, 21 and includes analysis of the X and Y sex chromosomes. Find out more

Downs Syndrome (Trisomy 21)
Patau’s Syndrome (Trisomy 13)
Edwards Syndrome (Trisomy 18)
X & Y
Gender Determination (optional)
Available from 10 Weeks
Results within 5 Working Days
Processed within the UK

TRIMESTER NIPT TEST THREE©

Trimester THREE gives you valuable information about the chromosomal status of the growing baby and screens all 24 chromosomes for the most common conditions, this includes analysis of chromosomes 9 and 16 which are known to cause intellectual and physical abnormalities and miscarriage.

Newer tests take advantage of next-generation sequencing (NGS) to bring a Whole Genome Sequencing (WGS) approach to NIPT, expanding test options beyond chromosomes 21, 18, and 13 to include rare autosomal aneuploidies (RAAs), sex chromosome aneuploidies (SCAs) and partial deletions and duplications.

Find out more.

All 24 Chromosomes
Downs Syndrome (Trisomy 21)
Patau’s Syndrome (Trisomy 13)
Edwards Syndrome (Trisomy 18)
Turners Syndrome (Monosomy X)
Klinefelter Syndrome Trisomy XXY)
Jacobs Syndrome (Trisomy XYY)
Trisomy X
Gender Determination (optional)
Available from 10 weeks
Results within 5 Working Days
Processed within the UK

TRIMESTER COMPLETE NIPT TEST

Trimester Complete is the most technologically advanced non-invasive prenatal test we offer. It is used to screen for several clinically significant and life-altering genetic disorders that are not tested for with current NIPT technology, allowing a more complete picture of the risk of a pregnancy being affected by a genetic disorder.

A customer may take a NIPT test for any reason, or if assessed as high risk due to:

Increased risk of miscarriage

History of miscarriage

Risk of Intra-Uterine Growth Restriction

A child affected with clotting disorders

Increased Nuchal fold

Referral where a NIPT test is recommended

Unknown family history

A previous pregnancy affected by genetic disease

Maternal age above 35 years old

High risk NHS combined test result

High risk PaPP-A

Anxiety or Reassurance purposes

Family History of a serious genetic condition

Advanced Paternal age

Or to screen for:

Cystic Fibrosis

Thalassemia-Beta

Sickle cell anaemia

Inherited Deafness

Trimester Complete also detects detects mutations in 4 genes causing 5 common Inherited and 44 severe Non-Inherited genetic disorders, 25 of these genes cause skeletal dysplasia, congenital heart defects, multiple congenital malformation syndromes and neuro-developmental disorders, such as autism and epilepsy.

By testing both parents DNA to achieve a wider testing profile for the most common genetic diseases

PrenatalSAFE NIPT Range

Choose from a full catalogue of tests that range from the basic NHS style test (PrenatalSAFE 3) to full karyotype and Genetic Screening for both parents.

Results are dependant on the depth and level of screening taken but can take from between 3 to 15 working days. (See below) Gender determination can be chosen.

PrenatalSAFE NIPT Catologue

Available from 10 weeks of pregnancy

Some test options are 'result ready' in as little as 3 Working Days *

Gender Determination (optional) - if you wan to plan a gender reveal event just let us know!

PrenatalSAFE can analyse multiple genes for mutations causing severe genetic disorders in pregnancy.

PrenatalSAFE offer a full range of screening options for chromosomal and Rare Autosomal Abnormalities, microdeletion syndromes and multiple genetic disorders.

PrenatalSAFE Genetic Screening is complementary to traditional and genome-wide NIPT that is not routinely analysed with some NIPT technology.

Gender Determination (optional)

Available from 10 weeks

PrenatalSAFE offer a full catalogue of tests that screen for chromosome, rare autosomal abnormalities (RAA's) and microdeletion syndromes.

PrenatalSAFE works as complementary screening for several life-altering genetic disorders that are not routinely analysed with current NHS technology, allowing for a clearer picture of the risk of your pregnancy being affected by genetic disorders.

Please read the accompanying leaflet carefully and choose the option that most suits you, your family or medical history.

Choose from:

PrenatalSAFE 3 - results in 3 working days
PrenatalSAFE 5- results in 3 working days
PrenatalSAFE 5 + DiGeorge - results in 10 working days
PrenatalSAFE PLUS - results in 10 working days
PrenatalSAFE Karyo - results in 10 woking days
PrenatalSAFE Karyo PLUS - results in 10 working days
PrenatalSAFE Complete - results in 15 working days
PrenatalSAFE Complete PLUS - results in 15 working days
PrenatalSAFE Full Risk - results in 15 working days
* Please read T & C's thoroughly

Book a NIPT Test

Pre-Test Information and Support

Our convenient online booking system is designed to give you the most information as possible and we answer any questions you may have.

NIPT Blood Test Appointment

Find your nearest recommended clinic, or arrange a home visit and relax in the comfort and privacy of your own home* (T&C's apply).

Courier Collection

Feel reasurred - All samples are collected by courier - No postal issues or delays involved.

Results Consultation

You can choose electronic reporting of your Laboratory results or they can be personally delivered by a medical professional, allowing time to ask questions and plan next steps.

Speak to a Midwife

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Terms and Conditions

Please read prior to booking

There are rare occasions where circumstances outside of our control can affect waiting times for laboratory reports and where results may be delayed or even need to be repeated.

Results are provided after laboratory analysis and wait times are given to you in 'working' days i.e. Monday to Friday. They do not include weekends or public holidays within the UK or EU.

The wait time begins after a sample has reached the processing laboratory, not from first day of transport.

Please remember, these are highly advanced medical tests, therefore the length of analysis is dependent on how your blood sample behaves under laboratory conditions.

Results cannot be accelerated or partially given in any circumstance.

In very rare circumstances where there is not enough cfDNA (from baby) in maternal blood, the sample may need to be repeated and analysed further.